RESEARCH OVERVIEW

Our lab uses molecular, cellular, and biochemical techniques to study neural crest formation in the chicken embryo to better understand overall animal growth and development.

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Migratory neural crest cells undergo EMT and give rise to a diverse array of structures in the developing vertebrate embryo.

Migratory neural crest cells undergo EMT and give rise to a diverse array of structures in the developing vertebrate embryo.

The Neural Crest

Known as the “fourth germ layer,” neural crest cells possess the capacity to differentiate into many cell types.

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Snail2 targets during neural crest cell EMT and migration

Snail2 represses many genes, including components of cell junctions, to mediate EMT.

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Neural crest cell interactions and the creation of the cranial ganglia

Neural crest cells must interact with placode cells to assemble the cranial ganglia.

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Lab News and Updates

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